ABSTRACT
Objective To explore the application of nerve ultrasound score (DCEC score) in the diagnosis of diabetic peripheral neuropathy. Methods Seventy－three patients with type 2 diabetes were divided into subclinical diabetic peripheral neuropathy group (n=16) and diabetic peripheral neuropathy group (n=58). DCEC score was obtained from all participants. The cut－off value of DCEC score was defined by the receiver operating characteristic (ROC) curve, and its sensitivity, specificity, accuracy, positive likelihood ratio and negative likelihood ratio were analyzed. Results When the DCEC score was ≥14.5, 50 cases of diabetic peripheral neuropathy were diagnosed. The sensitivity was 81.0% , the specificity was 80.0% , the accuracy was 80.8% , the positive likelihood ratio was 4.05, and the negative likelihood ratio was 0.24. Conclusion DCEC score can effectively diagnose diabetic peripheral neuropathy which can be used as a new method to diagnose diabetic peripheral neuropathy.
ABSTRACT
ObjectiveTo study the risk factors for children with incomplete Kawasaki disease(IKD) to decrease the development of coronary artery lesions (CAL).MethodsAll children diagnosed as IKD from Jan.2005 to Apr.2011 in our department were reviewed retrospectively for their clinical data,laboratory values and treatment measures.ResultsEight of the children (8/36,22.2％ ) were positive for CAL.The count of white blood cell( WBC),count of platelet(PLT),hematocrit and C reactive protein(CRP) level were ( 18.36 ± 4.63) × 109/L,(450.30 ± 155.40) × 109/L,( 25.63 ± 3.53 ),( 18.30 ± 3.80) mg/L and ( 13.48 ±3.27) × 109/L,(350.60 ± 56.80) × 109/L,( 33.78 ± 2.24 ),(9.70 ± 2.50) mg/L in the CAL group and non-CAL group respectively.And there were significant differences on the four indexes between CAL group and non-CAL group ( t =2.58,2.65,2.73,2.48,respectively,P ＜ 0.05 ).Pyretolysis time of children first undergoing globulin treatment was (2.5 ± 1.5 ) d and ( 1.5 ± 1.0 ) d in children under 1-year old and those above l-year old respectively,and the difference was significant ( t =2.35,P ＜ 0.05).ConclusionCAL should be cautiously prevented in IKD infants under l-year old with a fever lasting for over 5 days,decreased hematocrit and elevated WBC count,PLT count,Hct and CRP.Infant IKD patients are not so sensitive to intravenous gamma globulin and tend to occur CAL.They should be given an early diagnosis and timely treatment.